ESR01 Jake Johnson
Host Institution
KUL
Researching (short)
Optimized production of 225Ac by the ISOL method for medical applications
Educational Background
MPhys with study in Europe, The University of Manchester
jake.johnson @ kuleuven.be
Biography

Jake received his Master’s degree from the University of Manchester in 2018. His research first involved investigating how bachelor’s students conceptualize quantum mechanics. He then developed theoretical statistical models to better understand the interplay of information and entropy in small systems where the law of large numbers does not apply, in both quantum and classical regimes.

Upon finishing his degree, Jake cycled 26,000km across Eurasia to raise money for a charity that provides support to children with limited mobility. He remains an active figure within the UK adventure community, where he enjoys sharing stories of his travels and gently encouraging people to get out of their comfort zones.

He then began looking for a project that would enable him to use his physics background for immediate societal benefit. This is when he discovered the LISA network. He is now happily studying the production of Ac-225 for medical applications at ISOL facilities. He hopes that his work will lead to an enhanced production efficiency of pure Ac-225 that will be delivered to medical researchers for clinical trials that are beginning to demonstrate the power of such radionuclides in Targeted Alpha Treatment of distributed cancers.

Research at LISA ITN

Study and optimize the extraction of 225Ac using the ISOL technique, by either its direct production or the production of precursors, towards a sustainable, large-scale production of this isotope for medical applications.

Impact of this research

Quantifying the properties for the production of actinium and radium ion beams by the ISOL technique; optimizing the target and ion source geometries to maximize the production and extraction of actinium; provide regular samples out of the CERN MEDICIS facility to seed medical research programs; devise a route towards the sustainable use of the ISOL technique for the production of medical-grade samples of 225Ac.